Even after your "clarification" you are still comparing apples to oranges. A mutual fund is a type of investment. An IRA (Roth or traditional) is a "bag" or holder to put a mutual fund (or stocks, bonds, CDs, money market account) into to get a tax advantage.
To compare apples to apples do you mean
Mutual fund in a taxable account vs mutual fund in a ROTH IRA?
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